Hypogonadism and its treatment in London

Male hypogonadism is a medical condition characterized by the body’s inability to produce adequate levels of testosterone, the hormone responsible for the development and maintenance of male characteristics and reproductive function. 

This condition can be caused by issues with the testicles (primary hypogonadism) or problems with the hypothalamus or pituitary gland (secondary hypogonadism), which are parts of the brain that signal the testicles to produce testosterone. 

Symptoms of male hypogonadism can include reduced libido, erectile dysfunction, decreased muscle mass and strength, increased body fat, osteoporosis, and infertility. The condition can be congenital, present from birth, or acquired later in life due to injury, infection, or other medical conditions. Treatment typically involves testosterone replacement therapy to normalize hormone levels and alleviate symptoms.

Testosterone replacement

Exogenous testosterone treatments are used to manage male hypogonadism by providing external sources of testosterone to compensate for the body’s inadequate production. The different forms of exogenous testosterone treatments include:

1. Testosterone Injections: Administered intramuscularly, these injections can be given every few weeks, depending on the specific formulation. Common forms include testosterone cypionate and testosterone enanthate.
2. Transdermal Patches: Applied to the skin, typically on the back, abdomen, upper arm, or thigh, these patches release testosterone steadily over time. They need to be replaced daily.
3. Topical Gels and Creams: Applied daily to clean, dry skin, usually on the shoulders, upper arms, or abdomen, these products provide a steady release of testosterone through the skin. 
4. Transbuccal Systems: These are small tablets that adhere to the upper gum or inner cheek and release testosterone directly into the bloodstream through the oral mucosa.
5. Pellets: Implanted under the skin, usually in the buttocks or abdominal area, these pellets release testosterone slowly over a period of months, typically three to six months.
6. Nasal Gels: Applied inside the nostrils, this form of testosterone gel is typically administered two to three times a day, offering an alternative for those who prefer not to use patches or injections.
7. Oral Capsules: While less commonly used due to potential liver toxicity, some oral formulations like testosterone undecanoate are available that bypass the liver through absorption in the lymphatic system.

Each treatment option has its own advantages and potential side effects, and the choice of treatment often depends on patient preference, medical history, and specific health considerations.

Hypogonadism and fertility:

Exogenous testosterone treatments will often completely stop sperm from being produced. If a man wants to improve testosterone levels and retain his fertility, Pippa can help with this using different forms of medication (clomiphene or HCG as examples). She has many years experience with this and will carefully monitor your hormones and semen analysis to ensure both are improving.